Polymer mucoadhesion

The success of many controlled drug release systems depends on their ability to adhere effectively to mucous membranes.

  • Interface analysis: we study the interaction between bioadhesive polymers and biological substrates to quantify the force and extent of contact.
  • TEM/SEM visualisation: we observe the conformational changes of the polymer in contact with the mucosa and its possible penetration into mucinic networks.
  • Drug delivery optimisation: we provide essential data for the design of vectors that maximise residence time at the site of action.